Mfsd1 Gene Summary [Rat]
Predicted to enable dipeptide uniporter activity and protein homodimerization activity. Predicted to be involved in dipeptide transmembrane transport from lysosomal lumen to cytosol; protein localization to lysosome; and protein stabilization. Predicted to be active in lysosomal membrane. Orthologous to human MFSD1 (major facilitator superfamily domain containing 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mfsd1 |
| Official Name | major facilitator superfamily domain containing 1 [Source:RGD Symbol;Acc:1305751] |
| Ensembl ID | ENSRNOG00000013790 |
| Bio databases IDs | |
| Aliases | major facilitator superfamily domain containing 1 |
| Synonyms | 1200003O06Rik, major facilitator superfamily domain containing 1, Minerva, RGD1305751, SMAP4 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Mfsd1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- phosphoglycerate transporter family protein
- amide transporter
- nitrite extrusion protein (nitrite facilitator)
- Sugar (and other) transporter
- Major Facilitator Superfamily
- protein homodimerization
- protein binding
- uniporter
- transporter
- D-galactonate transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- lysosome
- lysosome membrane
- podocyte slit diaphragm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Mfsd1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- dipeptide transmembrane transport
- protein stabilization
Cellular Component
Where in the cell the gene product is active
- lysosomal membrane
- lysosome
Molecular Function
What the gene product does at the molecular level
- protein homodimerization activity