Mplkip Gene Summary [Rat]
Predicted to be located in Golgi apparatus and nucleoplasm. Predicted to be active in centrosome; midbody; and nucleus. Human ortholog(s) of this gene implicated in nonphotosensitive trichothiodystrophy 4. Orthologous to human MPLKIP (M-phase specific PLK1 interacting protein). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mplkip |
| Official Name | M-phase specific PLK1 interacting protein [Source:RGD Symbol;Acc:1584365] |
| Ensembl ID | ENSRNOG00000013806 |
| Bio databases IDs | |
| Aliases | M-phase specific PLK1 interacting protein |
| Synonyms | 2810021B07Rik, ABHS, C330007M08Rik, C7orf11, LOC678905, M-phase specific PLK1 interacting protein, M-phase specific PLK1 intereacting protein, ORF20, TTD4, Ttdn1 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Mplkip often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- M-phase-specific PLK1-interacting protein
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- intracellular membrane-bounded organelle
- Cytoplasm
- centrosome
- Golgi Apparatus
- midbody
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Mplkip gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell division
Cellular Component
Where in the cell the gene product is active
- nucleus
- centrosome
- cytoplasm
- intracellular membrane-bounded organelle
- Golgi apparatus
- midbody
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding