Cwf19l1 Gene Summary [Rat]
Predicted to enable RNA lariat debranching enzyme activator activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be part of post-mRNA release spliceosomal complex. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 17. Orthologous to human CWF19L1 (CWF19 like cell cycle control factor 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cwf19l1 |
| Official Name | CWF19 like cell cycle control factor 1 [Source:RGD Symbol;Acc:1304716] |
| Ensembl ID | ENSRNOG00000012763 |
| Bio databases IDs | |
| Aliases | CWF19 like cell cycle control factor 1 |
| Synonyms | C19L1, CWF19 like cell cycle control factor 1, hDrn1, SCAR17 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cwf19l1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Protein similar to CwfJ C-terminus 2
- protein binding
- metallophosphatase superfamily, metallophosphatase domain
- HIT_like
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Unknown
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Cwf19l1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- nuclear mRNA splicing, via spliceosome
Cellular Component
Where in the cell the gene product is active
- post-mRNA release spliceosomal complex
Molecular Function
What the gene product does at the molecular level
- protein binding