Slc30a7 Gene Summary [Rat]
Predicted to enable identical protein binding activity and zinc ion transmembrane transporter activity. Predicted to be involved in intracellular zinc ion homeostasis and zinc ion import into Golgi lumen. Predicted to act upstream of or within zinc ion transport. Located in Golgi cis cisterna membrane; mitochondrion; and sarcoplasmic reticulum membrane. Orthologous to human SLC30A7 (solute carrier family 30 member 7). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Slc30a7 |
| Official Name | solute carrier family 30 member 7 [Source:RGD Symbol;Acc:1307873] |
| Ensembl ID | ENSRNOG00000013912 |
| Bio databases IDs | |
| Aliases | solute carrier family 30 member 7 |
| Synonyms | 1810059J10Rik, 2610034N15Rik, 4833428C12Rik, solute carrier family 30 member 7, solute carrier family 30 (zinc transporter), member 7, ZHS, ZNT7, ZnTL2 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Slc30a7 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- cation diffusion facilitator family transporter
- zinc ion transporter
- Cation efflux family
- identical protein binding
- transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- insulin resistance
- Ziegler-Huang syndrome
- zinc deficiency
- Joubert syndrome type 1
- multiple sclerosis
- hyperglycemia
- weight gain
- hypopigmentation
role in cell
- expression in
- phosphorylation in
- quantity
- development
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- perinuclear region
- sarcoplasmic reticulum
- vesicles
- Golgi Apparatus
- Mitochondria
- cytoplasmic vesicles
- Golgi cisternae
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Slc30a7 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cellular zinc ion homeostasis
Cellular Component
Where in the cell the gene product is active
- perinuclear region of cytoplasm
- cytoplasm
- mitochondrion
- vesicle
- cytoplasmic vesicle
- Golgi membrane
- Golgi apparatus
- sarcoplasmic reticulum membrane
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- zinc ion transmembrane transporter activity