Lrp11 Gene Summary [Rat]

Predicted to enable phosphoprotein binding activity. Predicted to be involved in several processes, including response to cold; response to heat; and response to water deprivation. Predicted to be located in membrane. Orthologous to human LRP11 (LDL receptor related protein 11). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Lrp11
Official Name
LDL receptor related protein 11 [Source:RGD Symbol;Acc:1308602]
Ensembl ID
ENSRNOG00000014303
Bio databases IDs NCBI: 292462 Ensembl: ENSRNOG00000014303
Aliases LDL receptor related protein 11
Synonyms 1700034J19RIK, 6330533B21, 9830160H19RIK, AC156391.4, bA350J20.3, LDL receptor related protein 11, LOC108348623, low density lipoprotein receptor-related protein 11, MANSC3
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Lrp11 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • PKD domain
  • MANEC domain
  • LDLa
  • phosphoprotein binding
  • Cadherin repeat-like domain
  • Repeats in polycystic kidney disease 1 (PKD1) and other proteins

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • lung squamous cell carcinoma
  • squamous cell lung cancer
  • mixed connective tissue disease
  • focal cortical dysplasia type I
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • cellular membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Lrp11 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • response to cold
  • response to heat
  • response to starvation
  • multicellular organismal response to stress
  • response to immobilization stress
  • response to water deprivation
  • response to mechanical stimulus

Cellular Component

Where in the cell the gene product is active
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • phosphoprotein binding

Gene-Specific Assays for Results You Can Trust

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