LRP11 Gene Summary [Human]

Enables phosphoprotein binding activity. Predicted to act upstream of or within several processes, including response to cold; response to immobilization stress; and response to water deprivation. Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
LRP11
Official Name
LDL receptor related protein 11 [Source:HGNC Symbol;Acc:HGNC:16936]
Ensembl ID
ENSG00000120256
Bio databases IDs NCBI: 84918 Ensembl: ENSG00000120256
Aliases LDL receptor related protein 11
Synonyms 1700034J19RIK, 6330533B21, 9830160H19RIK, AC156391.4, bA350J20.3, LDL receptor related protein 11, LOC108348623, low density lipoprotein receptor-related protein 11, MANSC3
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human LRP11 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • PKD domain
  • MANEC domain
  • LDLa
  • phosphoprotein binding
  • Cadherin repeat-like domain
  • Repeats in polycystic kidney disease 1 (PKD1) and other proteins

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • lung squamous cell carcinoma
  • squamous cell lung cancer
  • mixed connective tissue disease
  • focal cortical dysplasia type I
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • cellular membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human LRP11 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • response to cold
  • response to heat
  • response to starvation
  • multicellular organismal response to stress
  • response to immobilization stress
  • response to water deprivation
  • response to mechanical stimulus

Cellular Component

Where in the cell the gene product is active
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • phosphoprotein binding

Gene-Specific Assays for Results You Can Trust

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