Osm

Predicted to enable cytokine activity; growth factor activity; and oncostatin-M receptor binding activity. Predicted to be involved in several processes, including oncostatin-M-mediated signaling pathway; positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction; and positive regulation of tyrosine phosphorylation of STAT protein. Predicted to act upstream of or within several processes, including positive regulation of macromolecule metabolic process; positive regulation of signal transduction; and tyrosine phosphorylation of STAT protein. Predicted to be located in extracellular space. Orthologous to human OSM (oncostatin M). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Osm often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Osm gene in rat plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the rat Osm gene, providing context for its role in the cell.