Atxn10 Gene Summary [Rat]
Enables enzyme binding activity and identical protein binding activity. Predicted to be involved in neuron projection development and regulation of cytokinesis. Predicted to act upstream of or within cilium assembly. Predicted to be located in several cellular components, including microtubule organizing center; midbody; and neuronal cell body. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 10. Orthologous to human ATXN10 (ataxin 10). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Atxn10 |
| Official Name | ataxin 10 [Source:RGD Symbol;Acc:621813] |
| Ensembl ID | ENSRNOG00000014637 |
| Bio databases IDs | |
| Aliases | ataxin 10 |
| Synonyms | ataxin 10, ATX10, C77170, E46, E46L, HUMEEP, SCA10, TEG-169, TEX169 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Atxn10 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Spinocerebellar ataxia type 10 protein domain
- enzyme binding
- protein binding
- identical protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- COVID-19
- spinocerebellar ataxia type 10
- Dupuytren contracture
- ulcerative colitis
- idiopathic scoliosis
role in cell
- proliferation
- binding in
- assembly
- morphogenesis
- O-GlcNAcylation in
- cytokinesis in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- soluble fraction
- cilia
- perinuclear region
- Nucleus
- Plasma Membrane
- basal bodies
- centriole
- midbody
- cytosol
- perikaryon
- dendrites
- cytosolic fraction
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Atxn10 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell division
- cilium morphogenesis
- neuron projection development
- regulation of cytokinesis
- nervous system development
Cellular Component
Where in the cell the gene product is active
- dendrite
- extracellular space
- perinuclear region of cytoplasm
- centriole
- cytoplasm
- cilium basal body
- membrane
- cytosol
- midbody
- neuronal cell body
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding