Gpr149

Predicted to enable G protein-coupled receptor activity and neuropeptide binding activity. Predicted to be involved in neuropeptide signaling pathway. Predicted to act upstream of or within antral ovarian follicle growth; negative regulation of ovulation; and preantral ovarian follicle growth. Predicted to be active in neuron projection and plasma membrane. Orthologous to human GPR149 (G protein-coupled receptor 149). [provided by Alliance of Genome Resources, Apr 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Gpr149 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Gpr149 gene in rat plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the rat Gpr149 gene, providing context for its role in the cell.