Gucy2e Gene Summary [Rat]
Enables guanylate cyclase activity and natriuretic peptide receptor activity. Involved in cGMP biosynthetic process and receptor guanylyl cyclase signaling pathway. Located in non-motile cilium and plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Gucy2e |
| Official Name | guanylate cyclase 2E [Source:RGD Symbol;Acc:69322] |
| Ensembl ID | ENSRNOG00000015058 |
| Bio databases IDs | |
| Aliases | guanylate cyclase 2E |
| Synonyms | Gc-d, guanylate cyclase 2d, guanylate cyclase 2E, Gucy2e, Gucy2ep, ONE-GC |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Gucy2e often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- natriuretic peptide receptor
- Receptor family ligand binding region
- Protein kinase (unclassified specificity)
- Protein tyrosine and serine/threonine kinase
- enzyme
- protein binding
- Serine/Threonine protein kinases, catalytic domain
- olfactory receptor
- Protein Kinases, catalytic domain
- Type 1 periplasmic binding fold superfamily
- guanylate cyclase
- Class III nucleotidyl cyclases
- Adenylyl- / guanylyl cyclase, catalytic domain
- Tyrosine kinase, catalytic domain
- odorant binding
Pathways
Biological processes and signaling networks where the Gucy2e gene in rat plays a role, providing insight into its function and relevance in health or disease.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- non-motile cilium
- cellular membrane