Cep72 Gene Summary [Rat]
Predicted to enable identical protein binding activity. Predicted to be involved in gamma-tubulin complex localization; microtubule cytoskeleton organization; and regulation of protein localization to centrosome. Predicted to be located in centrosome; ciliary basal body; and cytosol. Predicted to be active in centriolar satellite. Orthologous to human CEP72 (centrosomal protein 72). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cep72 |
| Official Name | centrosomal protein 72 [Source:RGD Symbol;Acc:1566336] |
| Ensembl ID | ENSRNOG00000015465 |
| Bio databases IDs | |
| Aliases | centrosomal protein 72 |
| Synonyms | 2610029E11Rik, 4933440J22Rik, centrosomal protein 72, RGD1566336 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cep72 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- occurring C-terminal to leucine-rich repeats
- Leucine rich repeat
- protein binding
- Leucine Rich repeats (2 copies)
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- esophageal adenocarcinoma
- esophageal carcinoma formation
- Barrett syndrome
- colorectal carcinomagenesis
- chromosomal instability
- androgenic alopecia
- rectum carcinoma
- rectum cancer
regulates
- BBSome
role in cell
- formation
- organization
- assembly
- formation in
- assembly in
- replication
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- basal bodies
- centrosome
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Cep72 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- spindle organization
- centriole replication
- gamma-tubulin complex localization
Cellular Component
Where in the cell the gene product is active
- centrosome
- centriolar satellite
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein binding