Abcc12 Gene Summary [Rat]
Predicted to enable ATPase-coupled transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in endoplasmic reticulum. Predicted to be active in membrane. Orthologous to human ABCC12 (ATP binding cassette subfamily C member 12). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Abcc12 |
| Official Name | ATP binding cassette subfamily C member 12 [Source:RGD Symbol;Acc:735100] |
| Ensembl ID | ENSRNOG00000015666 |
| Bio databases IDs | |
| Aliases | ATP binding cassette subfamily C member 12 |
| Synonyms | ATP binding cassette subfamily C member 12, MRP9 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Abcc12 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- lipid A export permease/ATP-binding protein MsbA
- heme ABC exporter, ATP-binding protein CcmA
- ABC transporter transmembrane region
- Six-transmembrane helical domain of the ATP-binding cassette transporters
- cystic fibrosis transmembrane conductor regulator (CFTR)
- thiol reductant ABC exporter, CydC subunit
- multi drug resistance-associated protein (MRP)
- nickel import ATP-binding protein NikE
- ABC transporter
- thiamine ABC transporter, ATP-binding protein
- ABC transporter, permease/ATP-binding protein
- P-loop containing Nucleoside Triphosphate Hydrolases
- transporter
- ATPases associated with a variety of cellular activities
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Endoplasmic Reticulum
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Abcc12 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- transmembrane transport
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- membrane
- endoplasmic reticulum
Molecular Function
What the gene product does at the molecular level
- ATPase activity
- ATP binding
- ATPase activity, coupled to transmembrane movement of substances