Cep85 Gene Summary [Rat]
Predicted to enable identical protein binding activity. Predicted to be involved in several processes, including centriole replication; negative regulation of protein kinase activity; and regulation of mitotic centrosome separation. Predicted to be located in several cellular components, including Golgi apparatus; microtubule cytoskeleton; and nucleolus. Predicted to be active in centrosome. Orthologous to human CEP85 (centrosomal protein 85). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cep85 |
| Official Name | centrosomal protein 85 [Source:RGD Symbol;Acc:1311520] |
| Ensembl ID | ENSRNOG00000016249 |
| Bio databases IDs | |
| Aliases | centrosomal protein 85 |
| Synonyms | 2410030J07RIK, CCDC21, centrosomal protein 85, LOC103694897, RGD1311520 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cep85 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- SPEC
- Protein-interacting V-domain of mammalian Alix and related domains
- Ciliary protein causing Leber congenital amaurosis disease
- Hyaluronan mediated motility receptor N-terminal
- Autophagy protein ATG17-like domain
- Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
- Growth-arrest specific micro-tubule binding
- Intermediate filament protein
- protein binding
- identical protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- intracellular membrane-bounded organelle
- cell cortex
- centrosome
- Golgi Apparatus
- centriole
- cytosol
- nucleoli
- spindle pole
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Cep85 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- centriole replication
- chromosome segregation
- negative regulation of protein kinase activity
- cell migration
- regulation of mitotic centrosome separation
Cellular Component
Where in the cell the gene product is active
- pericentriolar material
- centrosome
- centriole
- cell cortex
- spindle pole
- cytosol
- Golgi apparatus
- nucleolus
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- protein binding