Sphkap Gene Summary [Rat]
Predicted to enable protein kinase A binding activity. Predicted to be located in Z disc. Predicted to be active in mitochondrion. Orthologous to human SPHKAP (SPHK1 interactor, AKAP domain containing). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Sphkap |
| Official Name | SPHK1 interactor, AKAP domain containing [Source:RGD Symbol;Acc:1311951] |
| Ensembl ID | ENSRNOG00000016388 |
| Bio databases IDs | |
| Aliases | SPHK1 interactor, AKAP domain containing |
| Synonyms | 4930544G21Rik, A930009L15Rik, AI852220, mKIAA1678, RGD1311951, SKIP, SPHK1 interactor, AKAP domain containing |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Sphkap often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein kinase A binding
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- metabolic syndrome X
- peripheral neuropathy
- schizophrenia
- non-insulin-dependent diabetes mellitus
role in cell
- cell viability
- growth
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- Z line
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Sphkap gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- mitochondrion
Molecular Function
What the gene product does at the molecular level
- protein binding
- protein kinase A binding