Mrps27 Gene Summary [Rat]

Predicted to enable rRNA binding activity and tRNA binding activity. Predicted to be involved in cell population proliferation and mitochondrial translation. Predicted to be located in cytoplasm and nucleolus. Predicted to be part of mitochondrial small ribosomal subunit. Predicted to be active in mitochondrion. Orthologous to human MRPS27 (mitochondrial ribosomal protein S27). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Mrps27
Official Name
mitochondrial ribosomal protein S27 [Source:RGD Symbol;Acc:1311829]
Ensembl ID
ENSRNOG00000017272
Bio databases IDs NCBI: 361883 Ensembl: ENSRNOG00000017272
Aliases mitochondrial ribosomal protein S27
Synonyms 2610028H14RIK, KIAA0264, mitochondrial ribosomal protein S27, mS27, S27mt
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Mrps27 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • tRNA binding
  • rRNA binding
  • Mitochondrial 28S ribosomal protein S27
  • ribosome binding
  • protein binding

Pathways

Biological processes and signaling networks where the Mrps27 gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • insulin resistance
  • acute myeloid leukemia
  • insomnia
regulated by
  • SNCA
  • Lmp2a
  • SAMMSON
  • beta-estradiol
  • TRAP1
  • C9orf72
  • tamoxifen
role in cell
  • quantity
  • proliferation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Mitochondria
  • mitochondrial matrix
  • mitochondrial inner membrane
  • nucleoli

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Mrps27 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • cell proliferation
  • positive regulation of mitochondrial translation
  • mitochondrial translation

Cellular Component

Where in the cell the gene product is active
  • cytoplasm
  • mitochondrion
  • mitochondrial small ribosomal subunit
  • nucleolus
  • mitochondrial inner membrane

Molecular Function

What the gene product does at the molecular level
  • mitochondrial ribosome binding
  • protein binding
  • rRNA binding
  • tRNA binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.