Mrps27 Gene Summary [Mouse]
Predicted to enable mitochondrial ribosome binding activity; rRNA binding activity; and tRNA binding activity. Predicted to be involved in cell population proliferation; mitochondrial translation; and positive regulation of mitochondrial translation. Located in mitochondrion. Is expressed in several structures, including alimentary system; extraembryonic component; gonad; nervous system; and sensory organ. Orthologous to human MRPS27 (mitochondrial ribosomal protein S27). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mrps27 |
| Official Name | mitochondrial ribosomal protein S27 [Source:MGI Symbol;Acc:MGI:1919064] |
| Ensembl ID | ENSMUSG00000041632 |
| Bio databases IDs | |
| Aliases | mitochondrial ribosomal protein S27 |
| Synonyms | 2610028H14RIK, KIAA0264, mitochondrial ribosomal protein S27, mS27, S27mt |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mrps27 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- tRNA binding
- rRNA binding
- Mitochondrial 28S ribosomal protein S27
- ribosome binding
- protein binding
Pathways
Biological processes and signaling networks where the Mrps27 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- mitochondrial matrix
- mitochondrial inner membrane
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Mrps27 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cell proliferation
- positive regulation of mitochondrial translation
- mitochondrial translation
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- mitochondrion
- mitochondrial small ribosomal subunit
- nucleolus
- mitochondrial inner membrane
Molecular Function
What the gene product does at the molecular level
- mitochondrial ribosome binding
- protein binding
- rRNA binding
- tRNA binding