Tmem50a Gene Summary [Rat]
This gene is located in the RH gene locus, between the RHD and RHCE genes. The function of its protein product is unknown; however, its sequence has potential transmembrane domains suggesting that it may be an integral membrane protein. Its position between the RH genes suggests that polymorphisms in this gene may be tightly linked to RH haplotypes and may contribute to selective pressure for or against certain RH haplotypes. [provided by RefSeq, Jul 2008]
Details
| Type | Protein Coding |
| Official Symbol | Tmem50a |
| Official Name | transmembrane protein 50A [Source:RGD Symbol;Acc:1305638] |
| Ensembl ID | ENSRNOG00000017279 |
| Bio databases IDs | |
| Aliases | transmembrane protein 50A |
| Synonyms | 3200001F09Rik, CAM, IFNRC, RGD1305638, SMP1, transmembrane protein 50A |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Tmem50a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Uncharacterized protein family (UPF0220)
- protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- Cytoplasm
- cellular membrane
- Endoplasmic Reticulum
- glial cell projections
- perikaryon
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Tmem50a gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- late endosome to vacuole transport via multivesicular body sorting pathway
Cellular Component
Where in the cell the gene product is active
- membrane
- endoplasmic reticulum
- neuronal cell body
Molecular Function
What the gene product does at the molecular level
- protein binding