Leprotl1 Gene Summary [Rat]
Predicted to enable identical protein binding activity. Predicted to be involved in late endosome to vacuole transport via multivesicular body sorting pathway and negative regulation of growth hormone receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in endosome. Orthologous to human LEPROTL1 (leptin receptor overlapping transcript like 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Leprotl1 |
| Official Name | leptin receptor overlapping transcript-like 1 [Source:RGD Symbol;Acc:1307168] |
| Ensembl ID | ENSRNOG00000012601 |
| Bio databases IDs | |
| Aliases | leptin receptor overlapping transcript-like 1 |
| Synonyms | 1110067H13Rik, 1520402O14Rik, HSPC112, leptin receptor overlapping transcript-like 1, My047, Vps55 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Leprotl1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Vacuolar protein sorting 55
- protein binding
- identical protein binding
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Leprotl1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of growth hormone receptor signaling pathway
- late endosome to vacuole transport via multivesicular body sorting pathway
Cellular Component
Where in the cell the gene product is active
- endosome
- membrane
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- protein binding