Imp3 Gene Summary [Rat]

This gene encodes the human homolog of the yeast Imp3 protein. The protein localizes to the nucleoli and interacts with the U3 snoRNP complex. The protein contains an S4 domain. [provided by RefSeq, Jul 2008]

Details

Type
Protein Coding
Official Symbol
Imp3
Official Name
IMP U3 small nucleolar ribonucleoprotein 3 [Source:RGD Symbol;Acc:1306825]
Ensembl ID
ENSRNOG00000017460
Bio databases IDs NCBI: 315697 Ensembl: ENSRNOG00000017460
Aliases IMP U3 small nucleolar ribonucleoprotein 3
Synonyms 1190002L16Rik, BRMS2, C15orf12, IMP3, U3 small nucleolar ribonucleoprotein, IMP U3 small nucleolar ribonucleoprotein 3, MRPS4, RGD1306825
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Imp3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • ribosomal protein uS4, eukaryotic/archaeal type
  • S4
  • S4 domain
  • S4 RNA-binding domain
  • coiled-coil domain
  • protein binding
  • Ribosomal protein S4/S9 N-terminal domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • non-insulin-dependent diabetes mellitus
  • systemic autoimmune syndrome
  • chronic periodontal disease
regulated by
  • BAG3
  • methylprednisolone
  • CD 437
  • camptothecin
  • ST1926

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • pre-ribosome
  • Nucleus
  • cytosol
  • nucleoplasm
  • nucleoli

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Imp3 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • maturation of SSU-rRNA
  • ribosomal small subunit biogenesis
  • rRNA processing

Cellular Component

Where in the cell the gene product is active
  • small-subunit processome
  • nucleus
  • Mpp10 complex
  • preribosome
  • nucleolus
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • RNA binding
  • protein binding
  • snoRNA binding
  • rRNA binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.