IMP3 Gene Summary [Human]
This gene encodes the human homolog of the yeast Imp3 protein. The protein localizes to the nucleoli and interacts with the U3 snoRNP complex. The protein contains an S4 domain. [provided by RefSeq, Jul 2008]
Details
| Type | Protein Coding |
| Official Symbol | IMP3 |
| Official Name | IMP U3 small nucleolar ribonucleoprotein 3 [Source:HGNC Symbol;Acc:HGNC:14497] |
| Ensembl ID | ENSG00000177971 |
| Bio databases IDs | |
| Aliases | IMP U3 small nucleolar ribonucleoprotein 3 |
| Synonyms | 1190002L16Rik, BRMS2, C15orf12, IMP3, U3 small nucleolar ribonucleoprotein, IMP U3 small nucleolar ribonucleoprotein 3, MRPS4, RGD1306825 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human IMP3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- ribosomal protein uS4, eukaryotic/archaeal type
- S4
- S4 domain
- S4 RNA-binding domain
- coiled-coil domain
- protein binding
- Ribosomal protein S4/S9 N-terminal domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- pre-ribosome
- Nucleus
- cytosol
- nucleoplasm
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human IMP3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- maturation of SSU-rRNA
- ribosomal small subunit biogenesis
- rRNA processing
Cellular Component
Where in the cell the gene product is active
- small-subunit processome
- nucleus
- Mpp10 complex
- preribosome
- nucleolus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding
- snoRNA binding
- rRNA binding