Imp3 Gene Summary [Mouse]
Predicted to enable snoRNA binding activity. Acts upstream of or within rRNA processing. Predicted to be located in nucleolus and nucleoplasm. Predicted to be part of Mpp10 complex and small-subunit processome. Orthologous to human IMP3 (IMP U3 small nucleolar ribonucleoprotein 3). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Imp3 |
| Official Name | IMP3, U3 small nucleolar ribonucleoprotein [Source:MGI Symbol;Acc:MGI:1916119] |
| Ensembl ID | ENSMUSG00000032288 |
| Bio databases IDs | |
| Aliases | IMP3, U3 small nucleolar ribonucleoprotein |
| Synonyms | 1190002L16Rik, BRMS2, C15orf12, IMP3, U3 small nucleolar ribonucleoprotein, IMP U3 small nucleolar ribonucleoprotein 3, MRPS4, RGD1306825 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Imp3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- ribosomal protein uS4, eukaryotic/archaeal type
- S4
- S4 domain
- S4 RNA-binding domain
- coiled-coil domain
- protein binding
- Ribosomal protein S4/S9 N-terminal domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- pre-ribosome
- Nucleus
- cytosol
- nucleoplasm
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Imp3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- maturation of SSU-rRNA
- ribosomal small subunit biogenesis
- rRNA processing
Cellular Component
Where in the cell the gene product is active
- small-subunit processome
- nucleus
- Mpp10 complex
- preribosome
- nucleolus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding
- snoRNA binding
- rRNA binding