Mrs2 Gene Summary [Rat]
Predicted to enable magnesium ion transmembrane transporter activity. Involved in lactate metabolic process. Located in mitochondrial inner membrane. Used to study demyelinating disease. Orthologous to human MRS2 (magnesium transporter MRS2). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mrs2 |
| Official Name | magnesium transporter MRS2 [Source:RGD Symbol;Acc:708529] |
| Ensembl ID | ENSRNOG00000017545 |
| Bio databases IDs | |
| Aliases | magnesium transporter MRS2 |
| Synonyms | Gm902, HPT, magnesium transporter MRS2, MRS2L, MRS2 magnesium transporter, RPT |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Mrs2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- metal ion transporter CorA-like divalent cation transporter superfamily
- protein binding
- magnesium ion transporter
- transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- mitochondrial inner membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Mrs2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- transmembrane transport
- mitochondrial magnesium ion transport
- lactate metabolic process
Cellular Component
Where in the cell the gene product is active
- mitochondrion
- mitochondrial inner membrane
Molecular Function
What the gene product does at the molecular level
- magnesium ion transmembrane transporter activity