Srpk3 Gene Summary [Rat]
Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in several processes, including muscle tissue development; regulation of mRNA processing; and spliceosomal complex assembly. Predicted to act upstream of or within protein phosphorylation and skeletal muscle tissue development. Predicted to be active in cytoplasm and nucleus. Orthologous to human SRPK3 (SRSF protein kinase 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Srpk3 |
| Official Name | SRSF protein kinase 3 [Source:RGD Symbol;Acc:727856] |
| Ensembl ID | ENSRNOG00000054548 |
| Bio databases IDs | |
| Aliases | SRSF protein kinase 3 |
| Synonyms | MSSK-1, serine/arginine-rich protein specific kinase 3, SRSF protein kinase 3, STK23, XLID114 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Srpk3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- kinase
- Serine/Threonine protein kinases, catalytic domain
- protein serine/threonine kinase
- Protein Kinases, catalytic domain
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- X-linked mental retardation
- centronuclear myopathy
- congenital myopathy
- productive infection by HIV-1
role in cell
- expression in
- growth
- proliferation
- differentiation
- degeneration
- signaling in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Srpk3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- regulation of mRNA processing
- skeletal muscle tissue development
- cell differentiation
- muscle tissue development
- peptidyl-serine phosphorylation
- intracellular signal transduction
- spliceosomal complex assembly
Cellular Component
Where in the cell the gene product is active
- nucleus
- cytoplasm
Molecular Function
What the gene product does at the molecular level
- ATP binding
- protein binding
- protein serine/threonine kinase activity