Cog4 Gene Summary [Rat]
Predicted to enable identical protein binding activity. Predicted to be involved in Golgi organization; Golgi vesicle transport; and glycosylation. Predicted to be located in Golgi membrane. Predicted to be part of Golgi transport complex. Human ortholog(s) of this gene implicated in Saul-Wilson syndrome and congenital disorder of glycosylation type IIj. Orthologous to human COG4 (component of oligomeric golgi complex 4). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cog4 |
| Official Name | component of oligomeric golgi complex 4 [Source:RGD Symbol;Acc:1310549] |
| Ensembl ID | ENSRNOG00000017745 |
| Bio databases IDs | |
| Aliases | component of oligomeric golgi complex 4 |
| Synonyms | CDG2J, COD1, component of oligomeric golgi complex 4, D8Ertd515e, SWILS |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cog4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- identical protein binding
- COG4 transport protein
- transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Golgi Apparatus
- Golgi membrane
- trans Golgi network
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Cog4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- glycosylation
- retrograde vesicle-mediated transport, Golgi to ER
- Golgi organization
- protein transport
- retrograde transport, vesicle recycling within Golgi
Cellular Component
Where in the cell the gene product is active
- Golgi transport complex
- cytosol
- Golgi membrane
- trans-Golgi network membrane
Molecular Function
What the gene product does at the molecular level
- protein binding