Rabep2 Gene Summary [Rat]
Predicted to enable GTPase activator activity and growth factor activity. Predicted to be involved in regulation of cilium assembly. Predicted to be located in Golgi apparatus; cytosol; and microtubule organizing center. Predicted to be active in intracellular membrane-bounded organelle. Biomarker of cocaine dependence and nicotine dependence. Orthologous to human RABEP2 (rabaptin, RAB GTPase binding effector protein 2). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rabep2 |
| Official Name | rabaptin, RAB GTPase binding effector protein 2 [Source:RGD Symbol;Acc:621416] |
| Ensembl ID | ENSRNOG00000018462 |
| Bio databases IDs | |
| Aliases | rabaptin, RAB GTPase binding effector protein 2 |
| Synonyms | 2610011A08Rik, FRA, LOC100360815, MP13, RABAPTIN5 β, rabaptin, RAB GTPase binding effector protein 2 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Rabep2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Rabaptin-like protein
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- intracellular membrane-bounded organelle
- basal bodies
- endosomes
- centrosome
- Golgi Apparatus
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Rabep2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- signal transduction
- cell projection organization
- protein transport
- endocytosis
Cellular Component
Where in the cell the gene product is active
- early endosome
- centrosome
- cilium basal body
- intracellular membrane-bounded organelle
- cytosol
Molecular Function
What the gene product does at the molecular level
- growth factor activity
- protein binding
- GTPase activator activity