Zfand2b

Predicted to enable K48-linked polyubiquitin modification-dependent protein binding activity and ubiquitin binding activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process; protein targeting to ER; and regulation of insulin-like growth factor receptor signaling pathway. Predicted to act upstream of or within SRP-dependent cotranslational protein targeting to membrane, translocation. Predicted to be located in membrane. Predicted to be part of proteasome complex. Predicted to be active in endoplasmic reticulum. Orthologous to human ZFAND2B (zinc finger AN1-type containing 2B). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Zfand2b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the rat Zfand2b gene, providing context for its role in the cell.