Abhd11 Gene Summary [Rat]
Predicted to enable carboxylic ester hydrolase activity and lipase activity. Predicted to be involved in lipid metabolic process. Predicted to be located in mitochondrial matrix. Predicted to be part of oxoglutarate dehydrogenase complex. Predicted to be active in mitochondrion. Orthologous to human ABHD11 (abhydrolase domain containing 11). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Abhd11 |
| Official Name | abhydrolase domain containing 11 [Source:RGD Symbol;Acc:1304681] |
| Ensembl ID | ENSRNOG00000018910 |
| Bio databases IDs | |
| Aliases | abhydrolase domain containing 11 |
| Synonyms | 1110054D16Rik, A630008N09RIK, Abhd11l1, abhydrolase domain containing 11, CLONE 23605, LOC686139, PP1226, WBSCR21 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Abhd11 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- alpha/beta hydrolase fold
- alpha/beta hydrolases
- Serine aminopeptidase, S33
- Alpha/beta hydrolase family
- Thioesterase domain
- lipase
- enzyme
- protein binding
- 3-oxoadipate enol-lactonase
Pathways
Biological processes and signaling networks where the Abhd11 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- mitochondrial matrix
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Abhd11 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cellular lipid metabolic process
Cellular Component
Where in the cell the gene product is active
- mitochondrial matrix
- oxoglutarate dehydrogenase complex
- mitochondrion
Molecular Function
What the gene product does at the molecular level
- lipase activity
- carboxylic ester hydrolase activity