Plekhj1 Gene Summary [Rat]

Predicted to be involved in endosome organization; receptor recycling; and retrograde transport, endosome to Golgi. Predicted to be located in cytosol. Predicted to be active in early endosome; recycling endosome; and trans-Golgi network. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
Plekhj1
Official Name
pleckstrin homology domain containing J1 [Source:RGD Symbol;Acc:1307213]
Ensembl ID
ENSRNOG00000019247
Bio databases IDs NCBI: 314634 Ensembl: ENSRNOG00000019247
Aliases pleckstrin homology domain containing J1
Synonyms 9530063M10Rik, GNRPX, pleckstrin homology domain containing, family J member 1, pleckstrin homology domain containing J1
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Plekhj1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • PH domain
  • protein binding
  • Pleckstrin homology-like domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • coronary artery disease
  • abdominal aortic aneurysm
regulated by
  • methamphetamine

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Plekhj1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • endosome organization
  • retrograde transport, endosome to Golgi
  • receptor recycling

Cellular Component

Where in the cell the gene product is active
  • early endosome
  • trans-Golgi network
  • cytosol
  • recycling endosome

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

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