Pskh1 Gene Summary [Rat]

Predicted to enable protein kinase activity. Predicted to act upstream of or within determination of left/right symmetry; heart development; and protein phosphorylation. Located in cytosol and nuclear speck. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
Pskh1
Official Name
protein serine kinase H1 [Source:RGD Symbol;Acc:1304648]
Ensembl ID
ENSRNOG00000019290
Bio databases IDs NCBI: 364993 Ensembl: ENSRNOG00000019290
Aliases protein serine kinase H1
Synonyms AW539964, b2b1230Clo, E130013P03, E130013P03Rik, PFIC13, protein serine kinase H1
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Pskh1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • kinase
  • Serine/Threonine protein kinases, catalytic domain
  • protein serine/threonine kinase
  • Protein kinase (unclassified specificity)
  • protein kinase
  • Protein Kinases, catalytic domain
  • Protein tyrosine and serine/threonine kinase
  • protein binding
  • Protein kinase domain
  • Tyrosine kinase, catalytic domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • progressive familial intrahepatic cholestasis type 13
  • idiopathic pulmonary fibrosis
  • metabolic syndrome X
  • congenital heart disease
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • cilia
  • Plasma Membrane
  • centrosome
  • cytosol
  • nuclear speckles

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Pskh1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • heart development
  • determination of left/right symmetry

Cellular Component

Where in the cell the gene product is active
  • endoplasmic reticulum membrane
  • centrosome
  • nuclear speck
  • cytosol
  • Golgi apparatus
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • ATP binding
  • protein binding
  • protein serine/threonine kinase activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.