Pskh1 Gene Summary [Mouse]
Enables protein kinase activity. Acts upstream of or within determination of left/right symmetry; heart development; and protein phosphorylation. Predicted to be located in cytosol and nuclear speck. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and hemolymphoid system gland. Orthologous to human PSKH1 (protein serine kinase H1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Pskh1 |
| Official Name | protein serine kinase H1 [Source:MGI Symbol;Acc:MGI:3528383] |
| Ensembl ID | ENSMUSG00000048310 |
| Bio databases IDs | |
| Aliases | protein serine kinase H1 |
| Synonyms | AW539964, b2b1230Clo, E130013P03, E130013P03Rik, PFIC13, protein serine kinase H1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Pskh1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- kinase
- Serine/Threonine protein kinases, catalytic domain
- protein serine/threonine kinase
- Protein kinase (unclassified specificity)
- protein kinase
- Protein Kinases, catalytic domain
- Protein tyrosine and serine/threonine kinase
- protein binding
- Protein kinase domain
- Tyrosine kinase, catalytic domain
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- cilia
- Plasma Membrane
- centrosome
- cytosol
- nuclear speckles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Pskh1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- heart development
- determination of left/right symmetry
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
- centrosome
- nuclear speck
- cytosol
- Golgi apparatus
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- ATP binding
- protein binding
- protein serine/threonine kinase activity