LOC103693999 Gene Summary [Rat]

This gene encodes a member of the monovalent cation:proton antiporter 2 (CPA2) family of transporter proteins. Members of this family typically couple the export of monovalent cations, such as potassium or sodium, to the import of protons across cellular membranes. Mutations in this gene have been identified in patients with a rare inherited vision defect, cornea guttata with anterior polar cataract. [provided by RefSeq, Mar 2017]

Details

Type
Protein Coding
Official Symbol
LOC103693999
Official Name
transmembrane and coiled-coil domain-containing protein 3 [Source:RGD Symbol;Acc:9333008]
Ensembl ID
ENSRNOG00000019346
Bio databases IDs NCBI: 103693999 NCBI: 306607 Ensembl: ENSRNOG00000019346
Aliases transmembrane and coiled-coil domain-containing protein 3
Synonyms B230339H12RIK, C13orf11, C87304, LOC103690105, RGD1306586, transmembrane and coiled-coil domains 3
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Loc103693999 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Sodium/hydrogen exchanger family
  • transporter, monovalent cation:proton antiporter-2 (CPA2) family
  • transporter

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Loc103693999 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • potassium ion transmembrane transport

Cellular Component

Where in the cell the gene product is active
  • membrane

Molecular Function

What the gene product does at the molecular level
  • potassium:hydrogen antiporter activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.