Tmco3 Gene Summary [Mouse]

Predicted to enable potassium:proton antiporter activity. Predicted to be involved in potassium ion transmembrane transport and proton transmembrane transport. Predicted to be located in membrane. Is expressed in several structures, including cardiovascular system; central nervous system; gut; male reproductive gland or organ; and respiratory system. Orthologous to human TMCO3 (transmembrane and coiled-coil domains 3). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Retained Intron
Official Symbol
Tmco3
Official Name
transmembrane and coiled-coil domains 3 [Source:MGI Symbol;Acc:MGI:2444946]
Ensembl ID
ENSMUSG00000038497
Bio databases IDs NCBI: 234076 Ensembl: ENSMUSG00000038497
Aliases transmembrane and coiled-coil domains 3
Synonyms B230339H12RIK, C13orf11, C87304, LOC103690105, RGD1306586, transmembrane and coiled-coil domains 3
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Tmco3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Sodium/hydrogen exchanger family
  • transporter, monovalent cation:proton antiporter-2 (CPA2) family
  • transporter

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Tmco3 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • potassium ion transmembrane transport

Cellular Component

Where in the cell the gene product is active
  • membrane

Molecular Function

What the gene product does at the molecular level
  • potassium:hydrogen antiporter activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.