Lrfn4 Gene Summary [Rat]
Predicted to be involved in regulation of postsynaptic density assembly; regulation of presynapse assembly; and synaptic membrane adhesion. Is active in postsynaptic density membrane. Orthologous to human LRFN4 (leucine rich repeat and fibronectin type III domain containing 4). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Lrfn4 |
| Official Name | leucine rich repeat and fibronectin type III domain containing 4 [Source:RGD Symbol;Acc:1585286] |
| Ensembl ID | ENSRNOG00000019356 |
| Bio databases IDs | |
| Aliases | leucine rich repeat and fibronectin type III domain containing 4 |
| Synonyms | BC023156, FIGLER6, leucine rich repeat and fibronectin type III domain containing 4, LOC684051, SALM3, SALM3. |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Lrfn4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein phosphatase 1 regulatory subunit 42
- FN3
- immunoglobulin domain
- Immunoglobulin like
- Leucine rich repeat
- Immunoglobulin I-set domain
- Leucine rich repeat C-terminal domain
- protein binding
- Leucine Rich repeats (2 copies)
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- glutaminergic synapse
- cell surface
- cellular membrane
- synaptic membrane
- synapse
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Lrfn4 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- plasma membrane
- cell surface
Molecular Function
What the gene product does at the molecular level
- protein binding