LRFN4 Gene Summary [Human]
Predicted to be involved in regulation of postsynaptic density assembly; regulation of presynapse assembly; and synaptic membrane adhesion. Predicted to be located in plasma membrane. Predicted to be active in GABA-ergic synapse; cell surface; and glutamatergic synapse. Predicted to be integral component of postsynaptic density membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Processed Transcript |
| Official Symbol | LRFN4 |
| Official Name | leucine rich repeat and fibronectin type III domain containing 4 [Source:HGNC Symbol;Acc:HGNC:28456] |
| Ensembl ID | ENSG00000173621 |
| Bio databases IDs | |
| Aliases | leucine rich repeat and fibronectin type III domain containing 4, fibronectin type III, immunoglobulin and leucine rich repeat domains 6 |
| Synonyms | BC023156, FIGLER6, leucine rich repeat and fibronectin type III domain containing 4, LOC684051, SALM3, SALM3. |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human LRFN4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein phosphatase 1 regulatory subunit 42
- FN3
- immunoglobulin domain
- Immunoglobulin like
- Leucine rich repeat
- Immunoglobulin I-set domain
- Leucine rich repeat C-terminal domain
- protein binding
- Leucine Rich repeats (2 copies)
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- glutaminergic synapse
- cell surface
- cellular membrane
- synaptic membrane
- synapse
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human LRFN4 gene, providing context for its role in the cell.
Cellular Component
Where in the cell the gene product is active
- plasma membrane
- cell surface
Molecular Function
What the gene product does at the molecular level
- protein binding