Ciao3

Predicted to enable 4 iron, 4 sulfur cluster binding activity and metal ion binding activity. Predicted to be involved in several processes, including intracellular oxygen homeostasis; iron-sulfur cluster assembly; and response to hypoxia. Predicted to act upstream of or within hematopoietic progenitor cell differentiation. Predicted to be part of cytosolic [4Fe-4S] assembly targeting complex. Orthologous to human CIAO3 (cytosolic iron-sulfur assembly component 3). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ciao3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Ciao3 gene in rat plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the rat Ciao3 gene, providing context for its role in the cell.