Mrps12 Gene Summary [Rat]

Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in mitochondrion. Predicted to be part of mitochondrial small ribosomal subunit. Predicted to be active in ribosome. Orthologous to human MRPS12 (mitochondrial ribosomal protein S12). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Mrps12
Official Name
mitochondrial ribosomal protein S12 [Source:RGD Symbol;Acc:1306221]
Ensembl ID
ENSRNOG00000019949
Bio databases IDs NCBI: 292758 Ensembl: ENSRNOG00000019949
Aliases mitochondrial ribosomal protein S12
Synonyms mitochondrial ribosomal protein S12, MPR-S12, MT-RPS12, RPMS12, RPS12, RPSM12, S12mt, uS12m
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Mrps12 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • structural constituent of ribosome
  • protein binding
  • Ribosomal_S12_like

Pathways

Biological processes and signaling networks where the Mrps12 gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • insulin resistance
  • chronic periodontal disease
  • bipolar disorder
  • infection by HIV-1
regulated by
  • 4EGI-1
  • beta-estradiol
  • U0126
  • tetradecanoylphorbol acetate
  • MOS
  • WWTR1
  • YAP1
  • VEGFA
  • GSKJ4
  • tetracycline

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • inner membrane
  • Mitochondria
  • mitochondrial matrix
  • mitochondrial inner membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Mrps12 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • mitochondrial translation
  • translation

Cellular Component

Where in the cell the gene product is active
  • mitochondrial ribosome
  • ribosome
  • mitochondrial small ribosomal subunit
  • mitochondrial inner membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • RNA binding
  • structural constituent of ribosome

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.