Dnajc18 Gene Summary [Rat]
Predicted to enable Hsp70 protein binding activity. Predicted to be involved in cellular response to misfolded protein and chaperone cofactor-dependent protein refolding. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human DNAJC18 (DnaJ heat shock protein family (Hsp40) member C18). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Dnajc18 |
| Official Name | DnaJ heat shock protein family (Hsp40) member C18 [Source:RGD Symbol;Acc:1310237] |
| Ensembl ID | ENSRNOG00000019995 |
| Bio databases IDs | |
| Aliases | DnaJ heat shock protein family (Hsp40) member C18 |
| Synonyms | 2700075B01RIK, AU041129, DnaJ heat shock protein family (Hsp40) member C18, RGD1310237 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Dnajc18 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- DnaJ domain
- DnaJ
- DnaJ molecular chaperone homology domain
- enzyme
- Domain of unknown function (DUF1977)
Pathways
Biological processes and signaling networks where the Dnajc18 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- endoplasmic reticulum membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Dnajc18 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- chaperone mediated protein folding requiring cofactor
- cellular response to misfolded protein
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
Molecular Function
What the gene product does at the molecular level
- Hsp70 protein binding