Tssk6 Gene Summary [Rat]

Predicted to enable ATP binding activity; magnesium ion binding activity; and protein serine/threonine kinase activity. Predicted to be involved in flagellated sperm motility; peptidyl-serine phosphorylation; and sperm DNA condensation. Predicted to be active in axonemal microtubule doublet inner sheath and sperm flagellum. Orthologous to human TSSK6 (testis specific serine kinase 6). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Tssk6
Official Name
testis-specific serine kinase 6 [Source:RGD Symbol;Acc:1559764]
Ensembl ID
ENSRNOG00000020599
Bio databases IDs NCBI: 290670 Ensembl: ENSRNOG00000020599
Aliases testis-specific serine kinase 6
Synonyms CT72, FKSG82, RGD1559764, SSTK, testis-specific serine kinase 6, TSK-6, TSSK4
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Tssk6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • kinase
  • Serine/Threonine protein kinases, catalytic domain
  • protein serine/threonine kinase
  • Protein kinase (unclassified specificity)
  • binding protein
  • Protein Kinases, catalytic domain
  • Protein tyrosine and serine/threonine kinase
  • ATP binding
  • protein binding
  • Protein kinase domain
  • magnesium ion binding
  • Tyrosine kinase, catalytic domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • oligozoospermia
  • asthenozoospermia
regulated by
regulates
  • peptide
role in cell
  • cell viability
  • replication in
  • condensation
  • tumorigenicity
  • abnormal morphology
  • motility

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • sperm tail

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Tssk6 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • sperm chromatin condensation
  • protein phosphorylation

Cellular Component

Where in the cell the gene product is active
  • nucleus

Molecular Function

What the gene product does at the molecular level
  • magnesium ion binding
  • ATP binding
  • protein binding
  • protein serine/threonine kinase activity

Gene-Specific Assays for Results You Can Trust

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