Prnd Gene Summary [Rat]

Predicted to enable copper ion binding activity. Predicted to be involved in acrosome reaction and intracellular copper ion homeostasis. Predicted to be located in external side of plasma membrane. Orthologous to human PRND (prion like protein doppel). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Prnd
Official Name
prion like protein doppel [Source:RGD Symbol;Acc:1306618]
Ensembl ID
ENSRNOG00000021260
Bio databases IDs NCBI: 113910 Ensembl: ENSRNOG00000021260
Aliases prion like protein doppel
Synonyms dJ1068H6.4, DOPPEL, DPL, prion like protein doppel, PrPLP
Species
Rat, Rattus norvegicus
OrthologiesHuman

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Prnd often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Prion/Doppel alpha-helical domain
  • copper ion binding
  • protein binding
  • Prion-like protein Doppel

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • tuberculosis
  • germ cell neoplasia
  • Ewing sarcoma
  • osteosarcomagenesis
  • ataxia
  • teratoma
  • aortic valve calcification
regulated by
regulates
  • Ca2+
role in cell
  • quantity
  • degeneration

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • cell surface
  • Extracellular Space
  • cellular membrane
  • flagella
  • plasma membrane extracellular face

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Prnd gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • cellular copper ion homeostasis
  • acrosome reaction
  • protein homooligomerization

Cellular Component

Where in the cell the gene product is active
  • external side of plasma membrane
  • extracellular region
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • copper ion binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.