Mtfr1 Gene Summary [Rat]

Predicted to be involved in aerobic respiration and mitochondrial fission. Predicted to be located in cytosol and plasma membrane. Predicted to be active in mitochondrion. Orthologous to human MTFR1 (mitochondrial fission regulator 1). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Mtfr1
Official Name
mitochondrial fission regulator 1 [Source:RGD Symbol;Acc:1304936]
Ensembl ID
ENSRNOG00000021359
Bio databases IDs NCBI: 311403 Ensembl: ENSRNOG00000021359
Aliases mitochondrial fission regulator 1
Synonyms 1300002C08Rik, 1700080D04Rik, 2810026O10Rik, 4930579E05Rik, CHPPR, FAM54A2, KIAA0009, mitochondrial fission regulator 1, RGD1304936
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Mtfr1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding
  • Mitochondrial fission regulator

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • lung adenocarcinoma formation
  • organismal death
  • lung adenocarcinoma
regulated by
  • SPOP
  • Influenza A virus (A/Bangkok/RX73(H3N2))
regulates
  • p38 MAPK
  • ERK1/2
  • AKT1
role in cell
  • proliferation
  • phosphorylation in
  • migration
  • invasion by
  • cisplatin sensitivity
  • respiration

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Plasma Membrane
  • Mitochondria
  • cytosol

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Mtfr1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • aerobic respiration
  • mitochondrion organization
  • mitochondrial fission

Cellular Component

Where in the cell the gene product is active
  • mitochondrion
  • cytosol
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.