Nob1 Gene Summary [Rat]
Predicted to enable RNA endonuclease activity. Predicted to be involved in maturation of SSU-rRNA. Predicted to act upstream of or within visual perception. Predicted to be located in nucleus. Predicted to be part of preribosome, small subunit precursor. Orthologous to human NOB1 (NIN1 (RPN12) binding protein 1 homolog). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Nob1 |
| Official Name | NIN1 (RPN12) binding protein 1 homolog [Source:RGD Symbol;Acc:735222] |
| Ensembl ID | ENSRNOG00000021890 |
| Bio databases IDs | |
| Aliases | NIN1 (RPN12) binding protein 1 homolog |
| Synonyms | 1700021I09Rik, ART-4, MST158, MSTP158, NIN1 (RPN12) binding protein 1 homolog, NIN1/RPN12 binding protein 1 homolog, NOB1P, PSMD8BP1 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Nob1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- PIN domain of ribonuclease
- Nin one binding (NOB1) Zn-ribbon like
- Putative WW-binding domain and destruction box
- Large family of predicted nucleotide-binding domains
- endoribonuclease
- enzyme
- protein binding
- PIN (PilT N terminus) domain: Superfamily
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
- Endoplasmic Reticulum
- cytosol
- nucleoplasm
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Nob1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- maturation of SSU-rRNA
- rRNA processing
- visual perception
Cellular Component
Where in the cell the gene product is active
- cytosol
- preribosome, small subunit precursor
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- metal ion binding
- endoribonuclease activity