Nob1 Gene Summary [Mouse]
Predicted to enable RNA endonuclease activity. Acts upstream of or within visual perception. Predicted to be located in cytoplasm and nucleolus. Predicted to be part of preribosome, small subunit precursor. Is expressed in nervous system and neural retina. Orthologous to human NOB1 (NIN1 (RPN12) binding protein 1 homolog). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Retained Intron |
| Official Symbol | Nob1 |
| Official Name | NIN1/RPN12 binding protein 1 homolog [Source:MGI Symbol;Acc:MGI:1914869] |
| Ensembl ID | ENSMUSG00000003848 |
| Bio databases IDs | |
| Aliases | NIN1/RPN12 binding protein 1 homolog |
| Synonyms | 1700021I09Rik, ART-4, MST158, MSTP158, NIN1 (RPN12) binding protein 1 homolog, NIN1/RPN12 binding protein 1 homolog, NOB1P, PSMD8BP1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Nob1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- PIN domain of ribonuclease
- Nin one binding (NOB1) Zn-ribbon like
- Putative WW-binding domain and destruction box
- Large family of predicted nucleotide-binding domains
- endoribonuclease
- enzyme
- protein binding
- PIN (PilT N terminus) domain: Superfamily
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
- Endoplasmic Reticulum
- cytosol
- nucleoplasm
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Nob1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- maturation of SSU-rRNA
- rRNA processing
- visual perception
Cellular Component
Where in the cell the gene product is active
- cytosol
- preribosome, small subunit precursor
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding
- metal ion binding
- endoribonuclease activity