Ube2u Gene Summary [Rat]

Predicted to enable ubiquitin conjugating enzyme activity. Predicted to be involved in DNA repair; proteasome-mediated ubiquitin-dependent protein catabolic process; and protein polyubiquitination. Predicted to be part of HULC complex. Orthologous to human UBE2U (ubiquitin conjugating enzyme E2 U). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Ube2u
Official Name
ubiquitin conjugating enzyme E2 U [Source:RGD Symbol;Acc:1565480]
Ensembl ID
ENSRNOG00000023895
Bio databases IDs NCBI: 500511 Ensembl: ENSRNOG00000023895
Aliases ubiquitin conjugating enzyme E2 U
Synonyms RGD1565480, ubiquitin conjugating enzyme E2 U, ubiquitin-conjugating enzyme E2U (putative)
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ube2u often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Ubiquitin-conjugating enzyme
  • UBCc_UEV
  • enzyme
  • protein binding

Pathways

Biological processes and signaling networks where the Ube2u gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • bacterial meningitis
regulated by
role in cell
  • G2/M phase
  • focus formation in
  • focus formation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Ube2u gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • protein ubiquitination

Molecular Function

What the gene product does at the molecular level
  • ATP binding
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.