Tyw1 Gene Summary [Rat]

Predicted to enable several functions, including 4 iron, 4 sulfur cluster binding activity; FMN binding activity; and metal ion binding activity. Predicted to be involved in tRNA processing. Predicted to be located in membrane. Orthologous to several human genes including TYW1 (tRNA-yW synthesizing protein 1 homolog). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Tyw1
Official Name
tRNA-yW synthesizing protein 1 homolog [Source:RGD Symbol;Acc:1310420]
Ensembl ID
ENSRNOG00000024352
Bio databases IDs NCBI: 304423 Ensembl: ENSRNOG00000024352
Aliases tRNA-yW synthesizing protein 1 homolog
Synonyms FLJ10900, LOC103690026, RGD1310420, RSAFD1, tRNA-yW synthesizing protein 1 homolog, TYW1A, YPL207W
Species
Rat, Rattus norvegicus
OrthologiesHuman

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Tyw1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Radical_SAM
  • Radical SAM superfamily
  • flavodoxin
  • wyosine biosynthesis protein TYW1
  • Wyosine base formation
  • NADPH-dependent FMN reductase

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • Alzheimer disease
  • idiopathic pulmonary fibrosis

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Tyw1 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • wybutosine biosynthetic process

Molecular Function

What the gene product does at the molecular level
  • FMN binding
  • metal ion binding
  • 4 iron, 4 sulfur cluster binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.