Mex3b Gene Summary [Rat]

Predicted to enable GTPase activating protein binding activity and RNA binding activity. Predicted to act upstream of or within several processes, including positive regulation of GTPase activity; positive regulation of phagocytosis; and protein localization to cell cortex. Predicted to be located in P-body; cytosol; and nucleoplasm. Orthologous to human MEX3B (mex-3 RNA binding family member B). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Mex3b
Official Name
mex-3 RNA binding family member B [Source:RGD Symbol;Acc:1306790]
Ensembl ID
ENSRNOG00000025142
Bio databases IDs NCBI: 308790 Ensembl: ENSRNOG00000025142
Aliases mex-3 RNA binding family member B
Synonyms 4931439A04Rik, M-04814, mex-3 RNA binding family member B, mKIAA2009, RKHD3, RNF195
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Mex3b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • kinase
  • K homology (KH) RNA-binding domain, type I
  • KH domain
  • RING finger (Really Interesting New Gene) domain and U-box domain superfamily
  • Ring finger
  • calcium ion binding
  • protein binding
  • K homology RNA-binding domain
  • Zinc finger, C3HC4 type (RING finger)
  • RNA binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • hyperplasia
  • oligozoospermia
regulated by
  • SCp2 cells
  • HOTAIR
  • MMP3
  • NOTCH
regulates
role in cell
  • phagocytosis by
  • dipeptide repeat protein sensitivity
  • abnormal morphology

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • cytoplasmic mRNA processing body
  • cytosol
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Mex3b gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • protein autophosphorylation
  • protein phosphorylation

Cellular Component

Where in the cell the gene product is active
  • cytoplasmic mRNA processing body
  • cytosol
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • RNA binding
  • protein binding
  • calcium ion binding

Gene-Specific Assays for Results You Can Trust

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