Snupn Gene Summary [Rat]
Predicted to enable RNA cap binding activity. Predicted to be involved in RNA import into nucleus; cytoskeleton organization; and protein tetramerization. Predicted to be located in cytosol; nucleoplasm; and plasma membrane. Predicted to be part of NLS-dependent protein nuclear import complex. Orthologous to human SNUPN (snurportin 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Snupn |
| Official Name | snurportin 1 [Source:RGD Symbol;Acc:1303191] |
| Ensembl ID | ENSRNOG00000005426 |
| Bio databases IDs | |
| Aliases | snurportin 1 |
| Synonyms | 0610031A09Rik, KPNBL, LGMDR29, RNUT1, Snupn1, Snurportin1 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Snupn often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Adenylation domain of proteins similar to ATP-dependent polynucleotide ligases
- RNA cap binding
- Snurportin1
- importin beta binding domain
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- osteoarthritis
- autosomal recessive limb-girdle muscular dystrophy 29
regulates
- MAPK4
- U1 snRNP
- U5 snRNP
role in cell
- organization
- premature senescence
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- Cytoplasm
- perinuclear region
- Plasma Membrane
- cytosol
- nuclear pores
- nucleoplasm
- cytoplasmic fraction
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Snupn gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- RNA import into nucleus
- snRNA import into nucleus
- protein import into nucleus
Cellular Component
Where in the cell the gene product is active
- cytosol
- NLS-dependent protein nuclear import complex
- plasma membrane
- nucleoplasm
- nuclear pore
Molecular Function
What the gene product does at the molecular level
- protein binding
- RNA cap binding