Mex3b Gene Summary [Mouse]
Enables GTPase activating protein binding activity. Acts upstream of or within several processes, including positive regulation of GTPase activity; positive regulation of phagocytosis; and protein localization to cell cortex. Predicted to be located in P-body; cytosol; and nucleoplasm. Is expressed in several structures, including alimentary system; brain; cartilage; cranium; and reproductive system. Orthologous to human MEX3B (mex-3 RNA binding family member B). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Mex3b |
| Official Name | mex3 RNA binding family member B [Source:MGI Symbol;Acc:MGI:1918252] |
| Ensembl ID | ENSMUSG00000057706 |
| Bio databases IDs | |
| Aliases | mex3 RNA binding family member B |
| Synonyms | 4931439A04Rik, M-04814, mex-3 RNA binding family member B, mKIAA2009, RKHD3, RNF195 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Mex3b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- kinase
- K homology (KH) RNA-binding domain, type I
- KH domain
- RING finger (Really Interesting New Gene) domain and U-box domain superfamily
- Ring finger
- calcium ion binding
- protein binding
- K homology RNA-binding domain
- Zinc finger, C3HC4 type (RING finger)
- RNA binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytoplasmic mRNA processing body
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Mex3b gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- protein autophosphorylation
- protein phosphorylation
Cellular Component
Where in the cell the gene product is active
- cytoplasmic mRNA processing body
- cytosol
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding
- calcium ion binding