Coa4 Gene Summary [Rat]

Predicted to be involved in mitochondrial cytochrome c oxidase assembly. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
Coa4
Official Name
cytochrome c oxidase assembly factor 4 homolog [Source:RGD Symbol;Acc:1562228]
Ensembl ID
ENSRNOG00000025385
Bio databases IDs NCBI: 499214 Ensembl: ENSRNOG00000025385
Aliases cytochrome c oxidase assembly factor 4 homolog
Synonyms 5330414O08Rik, CHCHD8, CMC3, cytochrome c oxidase assembly factor 4, cytochrome c oxidase assembly factor 4 homolog, E2IG2, RGD1562228
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Coa4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • CXC motif
  • CHCH domain
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • chromophobe renal cell carcinoma
  • chromophobe renal cancer
regulated by
  • lipopolysaccharide
  • beta-estradiol
  • TSPO
  • levodopa
  • myoblasts
  • GSKJ4
  • SOCS1
role in cell
  • autophagy
  • autophagy in

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Mitochondria

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Coa4 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • mitochondrial respiratory chain complex IV assembly

Cellular Component

Where in the cell the gene product is active
  • mitochondrial intermembrane space
  • mitochondrion

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.