Coa4 Gene Summary [Mouse]
Predicted to be involved in mitochondrial cytochrome c oxidase assembly. Predicted to be located in mitochondrion. Predicted to be active in mitochondrial intermembrane space. Orthologous to human COA4 (cytochrome c oxidase assembly factor 4 homolog). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Retained Intron |
| Official Symbol | Coa4 |
| Official Name | cytochrome c oxidase assembly factor 4 [Source:MGI Symbol;Acc:MGI:1915435] |
| Ensembl ID | ENSMUSG00000044881 |
| Bio databases IDs | |
| Aliases | cytochrome c oxidase assembly factor 4 |
| Synonyms | 5330414O08Rik, CHCHD8, CMC3, cytochrome c oxidase assembly factor 4, cytochrome c oxidase assembly factor 4 homolog, E2IG2, RGD1562228 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Coa4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- CXC motif
- CHCH domain
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Coa4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- mitochondrial respiratory chain complex IV assembly
Cellular Component
Where in the cell the gene product is active
- mitochondrial intermembrane space
- mitochondrion