Cox11

Predicted to enable copper ion binding activity. Predicted to be involved in ATP biosynthetic process and intracellular monoatomic cation homeostasis. Predicted to act upstream of or within negative regulation of glucokinase activity. Predicted to be located in mitochondrion. Predicted to be part of protein-containing complex. Predicted to be active in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in mitochondrial complex IV deficiency nuclear type 23. Orthologous to human COX11 (cytochrome c oxidase copper chaperone COX11). [provided by Alliance of Genome Resources, Jul 2025]

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cox11 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.

Biological processes and signaling networks where the Cox11 gene in rat plays a role, providing insight into its function and relevance in health or disease.

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.

Describes the biological processes, cellular components, and molecular functions associated with the rat Cox11 gene, providing context for its role in the cell.